As a specialist supplier Fa. PURIMEX has a variety of modifications in the program. The synthons are either produced in our own building block synthesis or purchased from reputable suppliers. For the sake of clarity, the products are innucleosidic and non-nucleosidic divided modifications, wherein the nucleosidic further divided into u DNA. RNA and after the heterocyclic bases A, G, C, T, I and U are ordered. The classification is not always unambiguously possible. If in doubt, please look on the internet to the structure. The delivery quantities can not be guaranteed as they depend on the ability of the modified coupling device and the number of modifications within an oligonucleotide. As a rule, but the quantities given in single and double HPLC purification can be achieved.
Season prices (prices with "*")
With exotic - or unstable in solution modules, we are forced to set a scaled price. In the table only the lowest price is shown and provided with a "*". This price is valid if you order the module 5x or multiples thereof, in one order. If less than 5 Couplings / order be ordered, so the prices are calculated using the following formula:
Price / clutch = 5x Season Price / Number of couplings per order
DNA modifications
2'-dA modifications
designation |
Price [euro] / clutch |
||
50 nmol |
200 nmol |
1000 nmol |
|
12 |
15 |
23 |
|
52 * |
65 * |
98 * |
|
104 * |
130 * |
195 * |
|
44 * |
55 * |
83 * |
|
40 * |
50 * |
75 * |
|
104 * |
130 * |
195 * |
|
104 * |
130 * |
195 * |
|
120 * |
150 * |
225 * |
|
52 * |
65 * |
98 * |
|
44 * |
55 * |
83 * |
|
34 * |
43 * |
65 * |
*: Season Price (explanation see above.)
2'-dG modifications
designation |
Price [euro] / clutch |
||
50 nmol |
200 nmol |
1000 nmol |
|
12 |
15 |
23 |
|
104 * |
130 * |
195 * |
|
36 * |
45 * |
68 * |
|
104 * |
130 * |
195 * |
|
104 * |
130 * |
195 * |
|
52 * |
65 * |
98 * |
|
216 * |
270 * |
405 * |
|
36 * |
45 * |
68 * |
|
104 * |
130 * |
195 * |
|
104 * |
130 * |
195 * |
|
104 * |
130 * |
195 * |
*: Season Price (explanation see above.)
2'-dC modifications
designation |
Price [euro] / clutch |
||
50 nmol |
200 nmol |
1000 nmol |
|
12 |
15 |
23 |
|
22 * |
28 * |
42 * |
|
88 * |
110 * |
165 * |
|
68 * |
85 * |
128 * |
|
60 * |
75 * |
113 * |
|
5-fluoro-2'-dC |
60 * |
75 * |
113 * |
5-hydroxy-2'-dC |
96 * |
120 * |
180 * |
5-hydroxymethyl-2'-dC |
160 * |
200 * |
300 * |
38 * |
48 * |
72 * |
|
68 * |
85 * |
128 * |
|
22 |
28 |
42 |
*: Season Price (explanation see above.)
2'-dT modifications
designation |
Price [euro] / clutch |
||
50 nmol |
200 nmol |
1000 nmol |
|
12 |
15 |
23 |
|
48 * |
60 * |
90 * |
|
76 * |
95 * |
143 * |
|
44 * |
55 * |
83 * |
|
104 * |
130 * |
195 * |
|
88 * |
110 * |
165 * |
|
4-triazolyl-dT |
36 * |
45 * |
68 * |
Thymidinglycol |
104 * |
130 * |
195 * |
*: Season Price (explanation see above.)
2'-dI modifications
designation |
Price [euro] / clutch |
||
50 nmol |
200 nmol |
1000 nmol |
|
12 |
15 |
23 |
|
2'-dI CPG (3'-end) |
22 |
28 |
42 |
56 * |
70 * |
105 * |
|
80 * |
100 * |
150 * |
*: Season Price (explanation see above.)
2'-du-modifications
designation |
Price [euro] / clutch |
||
50 nmol |
200 nmol |
1000 nmol |
|
12 |
15 |
23 |
|
2'-du CPG (3'-end) |
28 |
35 |
53 |
22 * |
28 * |
42 * |
|
104 * |
130 * |
195 * |
|
42 * |
53 * |
80 * |
|
5-hydroxymethyl-2'-dU |
64 * |
80 * |
120 * |
35 * |
44 * |
66 * |
|
84 * |
105 * |
158 * |
|
72 * |
90 * |
135 * |
|
4-triazolyl-2'-dU |
36 * |
45 * |
68 * |
*: Season Price (explanation see above.)
RNA Modifications
rA-modifications
designation |
Price [euro] / clutch |
|
200 nmol |
1000 nmol |
|
2 ', 5'-rA |
16 |
24 |
27 |
41 |
|
5 |
8th |
|
127 * |
191 * |
|
105 * |
158 * |
|
2-Amino-rA |
119 * |
179 * |
134 * |
201 * |
|
62 * |
93 * |
|
49 * |
74 * |
|
115 * |
173 * |
|
139 * |
209 * |
|
62 |
93 |
*: Season Price (explanation see above.)
rG modifications
designation |
Price [euro] / clutch |
|
200 nmol |
1000 nmol |
|
2 ', 5'-rG |
16 |
24 |
27 |
41 |
|
5 |
8th |
|
127 * |
191 * |
|
134 * |
201 * |
*: Season Price (explanation see above.)
rC modifications
designation |
Price [euro] / clutch |
|
200 nmol |
1000 nmol |
|
2 ', 5'-rC |
16 |
24 |
94 * |
141 * |
|
9 |
14 |
|
5 |
8th |
|
57 * |
86 * |
|
55 * |
83 * |
|
55 * |
83 * |
|
99 * |
149 * |
|
62 * |
93 * |
|
I so RC |
134 * |
201 * |
50 * |
75 * |
*: Season Price (explanation see above.)
rU-modifications
designation |
Price [euro] / clutch |
|
200 nmol |
1000 nmol |
|
2 ', 5'-rU |
16 |
24 |
84 * |
126 * |
|
8th |
12 |
|
5 |
8th |
|
57 * |
86 * |
|
129 * |
194 * |
|
50 * |
75 * |
|
62 * |
93 * |
|
95 * |
143 * |
|
62 * |
93 * |
|
59 * |
89 * |
|
127 * |
191 * |
*: Season Price (explanation see above.)
RT modifications
designation |
Price [euro] / clutch |
|
200 nmol |
1000 nmol |
|
72 * |
108 * |
|
N3-methyl-RT |
70 * |
105 * |
*: Season Price (explanation see above.)
RI modifications
designation |
Price [euro] / clutch |
|
200 nmol |
1000 nmol |
|
13 |
20 |
|
50 * |
75 * |
*: Season Price (explanation see above.)
designation |
Price [euro] / clutch |
||
50 nmol |
200 nmol |
1000 nmol |
|
Acridine (5 'end) |
88 * |
110 * |
165 * |
54 |
68 |
102 |
|
12 |
15 |
23 |
|
Aminolinker C6 CPG (3'-end) |
23 |
29 |
44 |
32 * |
40 * |
60 * |
|
64 * |
80 * |
120 * |
|
Aminolinker C6-2'-dG |
136 * |
170 * |
255 * |
Aminolinker C6-2'-dC |
68 |
85 |
128 |
Aminolinker TEG N4-2'-dC |
36 * |
45 * |
68 * |
Aminolinker C6-2'-dC CPG |
54 |
68 |
102 |
Aminolinker C6-2' dT |
44 |
55 |
83 |
45 |
57 |
86 |
|
Aminolinker C6-Ru |
- |
250 |
375 |
22 |
28 |
42 |
|
Cholesterol (5 'end) |
82 * |
103 * |
155 * |
52 |
65 |
98 |
|
32 * |
40 * |
60 * |
|
38 * |
48 * |
72 * |
|
32 |
40 |
60 |
|
86 |
108 |
162 |
|
42 * |
53 * |
80 * |
|
32 |
40 |
60 |
|
42 * |
53 * |
80 * |
|
32 |
40 |
60 |
|
Phosphate (5'-end) |
12 |
15 |
23 |
34 |
43 |
65 |
|
52 * |
65 * |
98 * |
|
58 * |
73 * |
110 * |
|
52 |
65 |
98 |
|
30 * |
38 * |
57 * |
|
Spacer C3 (propanol) |
30 * |
38 * |
57 * |
30 * |
38 * |
57 * |
|
30 * |
38 * |
57 * |
|
28 * |
35 * |
53 * |
|
30 * |
38 * |
57 * |
|
28 * |
35 * |
53 * |
|
30 * |
38 * |
57 * |
|
30 * |
38 * |
57 * |
|
Thiol (5 'end) *** |
24 |
30 |
45 |
36 |
45 |
68 |
*: Season Price (explanation see above.)
**: NHS-C10 linker only in conjunction with non-aqueous oxidation
***: Thiol linker technical reasons only in conjunction with double HPLC purification. With the simultaneous presence of a thiol and a 3-fold Aminolinkers HPLC is required